BF-175 is a selective SIRT1 agonist. BF175 increases SIRT1-mediated activation of PGC1-α , induces Apoptosis , induces Autophagy and inhibits SREBP activity. BF-175 protects against high glucose-mediated mitochondrial injury. BF-175 attenuates diabetic kidney disease progression. BF175 inhibits endometrial carcinoma.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Fatty Acid Synthase (FASN) | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > PGC-1α | Products > Signaling Pathways > Apoptosis
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