Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel ( HY-B0015 ) conjugated to 1,18-octadecanedioic acid ( HY-W005178 ). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells ( IC 50 s = 12, 2.48, 8.62, and 64.42 nM, respectively).
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