PD0166285 dihydrochloride, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC 50 values of 24 and 72 nM, respectively. PD0166285 dihydrochloride exhibits an IC 50 of 3.433 μM for Chk1 .
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Wee1 | Products > Signaling Pathways > Apoptosis
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