CDK12-IN-4

Overview

CDK12-IN-4, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC 50 of 0.641 μM at high ATP (2 mM). CDK12-IN-4 has no effect on CDK2/Cyclin E (IC 50 >20 μM) and CDK9/Cyclin T1 (IC 50 >20 μM) at high ATP (2 mM) (WO2021116178A1).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-139327
• CAS No.: 2651196-69-7
• Molecular Formula: C20H20F2N8O
• Molecular Weight: 426.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source