(R)-Pioglitazone ((+)-pioglitazone) is the R enantiomer of Pioglitazone ( HY-13956 ). (R)-Pioglitazone is an orally active and selective peroxisome proliferator-activated receptor ( PPARγ ) agonist with high affinity binding to the PPARγ ligand-binding domain. (R)-Pioglitazone can be used for the research of Alzheimer's disease.
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