BIIB091

Overview

BIIB091 is a potent, selective, orally active and reversible BTK inhibitor, with an IC 50 of <0.5 nM. BIIB091 binds the BTK protein to sequester TYR-551 into an inactive conformation with excellent affinity. BIIB091 can be used for the research of multiple sclerosis.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Btk

Product Information

• Catalog No.: HY-139984
• CAS No.: 2247614-80-6
• Molecular Formula: C28H34N10O2
• Molecular Weight: 542.64
• Purity: 99.85%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.83 mM); Clear solution
• Availability: In-stock

Source

Original product source