Compound E

Overview

Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC 50 s of 0.24, 0.37, 0.32 nM, respectively.

Application

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Product Information

• Catalog No.: HY-14176
• CAS No.: 209986-17-4
• Molecular Formula: C27H24F2N4O3
• Molecular Weight: 490.50
• Purity: 99.97%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.88 mg/mL (5.87 mM); Clear solution
• Availability: In-stock

Source

Original product source