ATX inhibitor 11 (compound 13c) is a potent ATX ( autotaxin ) inhibitor, with an IC 50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research.
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