FAUC 213 is an orally active and highly selective dopamine D 4 receptor complete antagonist with a K i of 2.2 nM for hD 4.4 . FAUC 213 has less activity on D 2 and D 3 receptors (K i s of 3.4 μM, 5.3 μM for hD 2 , hD 3 , respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic.
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