GSK-9772

Overview

GSK-9772 is a Liver X Receptor ( LXR ) modulator of the N-phenyl tertiary amine class (NPTAs) with high affinity for LXR β ligand ( IC 50 =30 nM). GSK-9772 has anti-inflammatory activity by binding to LXR , specifically by interacting with the region associated with the transcriptional repression function of the receptor, thereby inhibiting the expression of pro-inflammatory genes. GSK-9772 can be used in the study of inflammatory and neurodegenerative diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LXR

Product Information

• Catalog No.: HY-14353
• CAS No.: 928035-84-1
• Molecular Formula: C20H19Cl2F6NO2
• Molecular Weight: 490.27
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source