Trk-IN-8 is a potent TRK inhibitor with IC 50 s of 0.42, 0.89 and 1.5 nM for TRKAa, TRKA (G595R) and TRKC (G623R), respectively (WO2021115401A1, compound 3).
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Trk Receptor
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