BTK-IN-7 is a potent and selective inhibitor of BTK ( IC 50 =4.0 nM). BTK-IN-7 has high selectivity in both enzymatic ( ITK >250-fold, EGFR >2500-fold) and cellular levels ( ITK >227-fold, EGFR 27-fold). BTK-IN-7 also has potent antitumor activity.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Btk | Products > Signaling Pathways > Apoptosis
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