AChE-IN-5 (compound 5) exhibits strong in vitro bioactivity against AChE/5-HT 1A /SERT and exhibits good BBB permeability. AChE-IN-5 shows IC 50 value 2.29 nM against AChE , EC 50 value 58.6 nM against 5-HT 1A and IC 50 value against SERT. Orally active.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Serotonin Transporter
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