AChE-IN-10 (Compound 24r) is a potent inhibitor of AChE ( IC 50 = 2.4 nM). AChE-IN-10 potently inhibits AChE , reduces tau phosphorylation at S396 residue, provides neuroprotection by rescuing neuronal morphology and increasing cell viability. AChE-IN-10 is also found to reduce amyloid aggregation in the presence of AChE .
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE)
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