AF-353

Overview

AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC 50 of 8.0 for both human and rat P2X3, and with a pIC 50 of 7.3 for human P2X2/3.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > P2X Receptor

Product Information

• Catalog No.: HY-14483
• CAS No.: 865305-30-2
• Molecular Formula: C14H17IN4O2
• Molecular Weight: 400.21
• Purity: 99.43%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.25 mM); Clear solution
• Availability: In-stock

Source

Original product source