TTBK1-IN-2

Overview

TTBK1-IN-2 (compound 29) is a potent Tau-Tubulin kinase (TTBK1) inhibitor with IC 50 s of 0.24 and 4.22 µM, respectively. TTBK1-IN-2 reveals good brain penetration in vivo and is able to reduce TDP-43 phosphorylation not only in cell cultures but also in the spinal cord of transgenic TDP-43 mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Tau Protein

Product Information

• Catalog No.: HY-145313
• CAS No.: 2765453-51-6
• Molecular Formula: C18H13ClN4O
• Molecular Weight: 336.78
• Purity: 99.91%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.42 mM); Clear solution
• Availability: In-stock

Source

Original product source