VU10010

Overview

VU10010 is a potent, highly selective and allosteric M 4 mAChR potentiator with an EC 50 of 400 nM. VU10010 binds to an allosteric site on M 4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR

Product Information

• Catalog No.: HY-14563
• CAS No.: 633283-39-3
• Molecular Formula: C17H16ClN3OS
• Molecular Weight: 345.85
• Purity: 98.04%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (6.01 mM); Clear solution
• Availability: In-stock

Source

Original product source