HDAC-IN-33 is a potent HDAC inhibitor with IC 50 s of 24, 46, and 47 nM for HDAC1 , HDAC2 and HDAC6 , respectively. HDAC-IN-33 possesses potent antiproliferation activities against tumor cells. HDAC-IN-33 shows potent antitumor efficacy in vivo That trigger antitumor immunity.
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