7α-Hydroxy-DHEA

Overview

7α-Hydroxy-DHEA (7α-Hydroxydehydroepiandrosterone) is a 7α-hydroxylated metabolite of DHEA ( HY-14650 ), catalyzed by intracellular steroid 7α-hydroxylases such as P450 2A1 . 7α-Hydroxy-DHEA exhibits biological activity comparable to DHEA but does not convert into compounds with androgenic or estrogenic activity. It induces the activity of thermogenic enzymes such as mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme , enhancing heat production and reducing food utilization efficiency. As a more efficient and safer metabolite compared to DHEA , 7α-Hydroxy-DHEA holds potential for studies in the fields of obesity, metabolic diseases, and adrenal carcinoma.

Application

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Product Information

• Catalog No.: HY-145751
• CAS No.: 53-00-9
• Molecular Formula: C19H28O3
• Molecular Weight: 304.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source