Dyrk1A-IN-5

Overview

Dyrk1A-IN-5 (Compound 5j) is a potent and selective DYRK1A inhibitor, with an IC 50 of 6 nM. yrk1A-IN-5 exhibits significant selectivity for DYRK1B ( IC 50 = 600 nM) and CLK1 ( IC 50 = 500 nM), but shows almost no inhibition of DYRK2 ( IC 50 > 10 μM). Dyrk1A-IN-5 can be used for Down syndrome research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > DYRK

Product Information

• Catalog No.: HY-146221
• CAS No.: 1685235-41-9
• Molecular Formula: C16H9IN2O2
• Molecular Weight: 388.16
• Purity: 98.06%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source