CDK/HDAC-IN-2

Overview

CDK/HDAC-IN-2 is a potent HDAC/CDK dual inhibitor with IC 50 of 6.4, 0.25, 45, >1000, 8.63, 0.30, >1000 nM for HDAC1 , HDAC2 , HDAC3 , HDAC6 ,8, CDK1 , CDK2 , CDK4 ,6,7, respectively. CDK/HDAC-IN-2 shows excellent antiproliferative activities. CDK/HDAC-IN-2 induces apoptosis and cell cycle arrest at G2/M phase. CDK/HDAC-IN-2 shows potent antitumor efficacy.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-146276
• CAS No.: 2580938-58-3
• Molecular Formula: C25H20Cl2N6O3
• Molecular Weight: 523.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source