MAO-B-IN-9

Overview

MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B ( monoamine oxidase B) inhibitor, with an IC 50 of 0.18 μM. MAO-B-IN-9 prevents Aβ 1-42 -induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ 1-42 anti-aggregation effects. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

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Product Information

• Catalog No.: HY-146314
• CAS No.: 2416910-88-6
• Molecular Formula: C18H24N2O2
• Molecular Weight: 300.40
• Purity: 99.70%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (8.32 mM); Clear solution
• Availability: In-stock

Source

Original product source