BRAF V600E/CRAF-IN-2

Overview

BRAF V600E/CRAF-IN-2 (Compound 9c) is a potent inhibitor of BRAF V600E / CRAF with IC 50 s of 0.888 and 0.229 μM, respectively. BRAF V600E/CRAF-IN-2 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-2 has the potential for the research of cancer diseases.

Application

Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Raf

Product Information

• Catalog No.: HY-146443
• CAS No.: 2499499-62-4
• Molecular Formula: C30H30F3N5O2
• Molecular Weight: 549.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source