EGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC 50 values of 0.358, 86.02 and 432.67 µM against EGFR , EGFR L858R-TK and EGFR T790M-TK , respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis .
Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Apoptosis
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