PARP10/15-IN-2 (Compound 8h) is a potent PARP10 and PARP15 dual inhibitor with IC 50 values of 0.15 µM and 0.37 µM against PARP10 and PARP15 , respectively. PARP10/15-IN-2 is able to enter cells and rescue cells from apoptosis .
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