Dabrafenib

Dabrafenib
  • CAS No.:1195765-45-7
  • Grade:99.94%
  • Formula:C23H20F3N5O2S2
  • M.W.:519.56
  • Solvent:≥ 2.5 mg/mL (4.81 mM); Clear solution

Overview

Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC 50 s of 5 nM and 0.6 nM for C-Raf and B-Raf V600E , respectively.

Application

Products | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Raf | Products > Signaling Pathways > CDK

Product Information

  • Catalog No.: HY-14660
  • CAS No.: 1195765-45-7
  • Molecular Formula: C23H20F3N5O2S2
  • Molecular Weight: 519.56
  • Purity: 99.94%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.5 mg/mL (4.81 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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