SB-743921 free base is a potent selective inhibitor of the mitotic kinesin KSP (Eg5) , with a K i of 0.1 nM. SB-743921 free base can induce mitotic arrest, block cell cycle progression, induce apoptosis , and can be used in the research of myeloma, leukemia and other diseases .
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Kinesin
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