EGFR-IN-49 is a potent and selective EGFR inhibitor with IC 50 s of 65.0 nM and 13.6 nM for EGFR T790M and EGFR T790M/L858R , respectively. EGFR-IN-49 induces late apoptosis in a dose-dependent manner.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR
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