ZMF-10 is a highly potent PAK1 inhibitor, with IC 50 s of 174 nM, 1.038 μM and 1.372 μM for PAK1 , PAK2 and PAK3 , respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis , ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PAK | Products > Signaling Pathways > Apoptosis
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