Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 ( Gal-3 ) antagonist with K d value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with K d values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively.
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