LCS3 is a reversible and uncompetitive glutathione disulfide reductase ( GSR ) and thioredoxin reductase 1 ( TXNRD1 ) inhibitor ( IC 50 =3.3 µM and 3.8 µM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis . LCS3 can be used in lung adenocarcinoma (LUAD) research.
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