ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC 50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC 50 of 37.34 nM. ATR-IN-18 has anti-tumor activity.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ATM/ATR
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