GABAA receptor modulator-2 (Compound 20) is selective, orally active α5-GABA A R negative allosteric modulator (NAM) with a K i of 4.1 nM. GABAA receptor modulator-2 shows high-metabolic stability and good CNS safety.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor
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