β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist ( MABA ). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC 50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a K i value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC 50 value of 4.0 nM.
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