OUL232 is a potent inhibitor of mono-ARTs PARP7 , PARP10 , PARP11, PARP12 , PARP14 , and PARP15 . OUL232 is the most potent PARP10 inhibitor described to date ( IC 50 =7.8 nM), as well as the first PARP12 inhibitor ever reported.
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