CHDI-00484077 (Compound 12) is a CNS-penetrant class IIa HDAC inhibitor, with IC 50 s of 0.01 μM ( HDAC4 ), 0.02 μM( HDAC5 ), 0.02 μM ( HDAC7 ), 0.03 μM ( HDAC9 ) respectively. CHDI-00484077 can be used for research of huntington’s disease.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HDAC
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