Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET) . Cavα2δ1&NET-IN-3 has K i s of 100-500 nM for human α2δ-1 subunit of Ca v 2.2 calcium channel and NET, respectively.
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