MR2938 is a potent AChE inhibitor, with an IC 50 of 5.04 μM. MR2938 also suppresses NO production obviously ( IC 50 = 3.29 μM). MR2938 suppresses the neuroinflammation through blocking MAPK/JNK and NF-κB signaling pathways. MR2938 can be used for Alzheimer’s disease (AD) research.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > CCR | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > JNK | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > NF-κB
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