Aβ-IN-7 (compound 5a) is a potent inhibitor of the Aβ aggregation . Aβ-IN-7 with 50 μM stabilize Aβ monomers in the small oligomeric species and prolong the nucleation process. Aβ-IN-7 inhibits Aβ fibril formation better than Aβ-IN-8 ( HY-149583 ) in 50 μM.
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