ICMT-IN-21 (compound 6ag) is an ICMT inhibitor ( IC 50 =8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT -IN-21 are important structures for inhibiting ICMT .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ICMT
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