HDAC-IN-57 is an orally active inhibitor of histone deacetylases ( HDAC ), with IC 50 s of 2.07 nM, 4.71 nM, 2.4 nM and 107 nM for HDAC1 , HDAC2 , HDAC6 , HDAC8 , respectively. HDAC-IN-57 can inhibits LSD1, with IC 50 of 1.34 μΜ. HDAC-IN-57 induces apoptosis , and has anti-tumor activity.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Histone Demethylase
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