IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC 50 : 67.4 nM, HeLa hIDO1 IC 50 : 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile.
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