(4aS,8aR)-NPD-001

Overview

(4aS,8aR)-NPD-001 is a potent and allosteric inhibitor of DNMT3A . (4aS,8aR)-NPD-001 inhibits DNMT3A activity by disrupting protein-protein interactions. (4aS,8aR)-NPD-001 induces apoptosis of acute myeloid leukemia (AML) cell lines. (4aS,8aR)-NPD-001 induces differentiation of distinct AML cell lines including cells with mutated DNMT3A R882.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA Methyltransferase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-150025
• CAS No.: 2366272-43-5
• Molecular Formula: C33H40N6O4
• Molecular Weight: 584.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source