JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC 50 values of >100, >100, 0.25 µM for JNK1 , JNK2 , JNK3 , respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition.
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Signaling Pathways > JNK | Products > Signaling Pathways > Discoidin Domain Receptor
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