JAK3-IN-13

Overview

JAK3-IN-13 (compound 12n) is a potent, selective and orally active JAK3 inhibitor with IC 50 values of 4728, 2039, 8, 365 nM for NK1, JNK2 , JNK3 , Tyk2 , respectively. JAK3-IN-13 shows antiproliferative activity. JAK3-IN-13 induces cell cycle arrest at G0/G1 phase. JAK3-IN-13 shows antitumor activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > JNK

Product Information

• Catalog No.: HY-150688
• CAS No.: 2803329-86-2
• Molecular Formula: C25H33ClN6O5
• Molecular Weight: 533.02
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source