EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR / HER2 kinase and DHFR inhibitor, with IC 50 s of 0.18 μM ( EGFR ), 0.146 μM ( HER2 ), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR ( IC 50 =0.907 μM).
Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR
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