NNMT-IN-3 (Compound 14) is a potent and selective nicotinamide N-methyltransferase ( NNMT ) inhibitor, with IC 50 values of 1.1 nM and 0.4 μM in cell-free and cell-based assays, respectively. NNMT-IN-3 can be used in the research of diseases such as obesity, type 2 diabetes and cancer .
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