ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 ( IC 50 =7.9 µM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 µM).
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cytochrome P450
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