ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor ( IC 50 ≤10 nM), inhibits TGF-β -induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer , fibrotic diseases, and systemic sclerosis.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor
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