AChE/BChE-IN-10 (Compound 7b) is a potent dual AChE and BChE inhibitor with IC 50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 shows good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation and be used in Alzheimer’s disease (AD) research.
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